Coronary CT angiography (CTA) is rapidly changing the patient-care algorithms used to detect coronary artery disease, as well as the approach we take in risk-factor assessment and in the triage of patients. The rapid adoption of coronary CTA into clinical practice has been fueled by significant yearly advances in CT technology, which have improved the spatial and temporal resolution of this technique while simultaneously decreasing radiation exposure.
The growing utilization of coronary CTA has created a need for comprehensive didactic texts that explain the numerous applications of this new technology with respect to the pathophysiology of coronary artery disease, while also providing information on the approach to patients who have undergone previous bypass surgery or percutaneous coronary intervention. This book accomplishes both of these goals, and does so in a reader-friendly format. The image quality of the many figures that accompany each chapter is excellent and reflects the use of state of the art technology. The techniques described for plaque detection and characterization represent the current thinking pervasive in the coronary CTA community. The comprehensive reference list at the end of the book offers the reader a wealth of resources for further study.
There is no doubt that this book will be popular with radiologists, cardiologists, CT technologists and anyone else seeking to acquire a comprehensive understanding of coronary artery disease and its depiction using coronary CTA.
Contents
1 Clinical Anatomy of the Coronary Circulation
- Angiographic Anatomy of the Coronary Circulation
- Intramyocardial Vascularization and the Venous Circulation
- Variability of the Coronary Artery Circulation
- Anomalous Coronary Arteries
- Factors Determining Coronary Artery Size
2 Basic Techniques in the Acquisition of Cardiac Images with CT
- Technical Principles in the Acquisition of Cardiac Images by CT
- From Conventional to Spiral CT
- From Spiral to Multislice CT
- Detector Number and Cardiac Imaging
- Temporal Resolution in Cardiac Imaging
- Types of Equipment and Their Clinical Uses in Cardiac Imaging
- Other Factors That Improve the Image Quality of CT Technology
3 CT Examination of the Coronary Arteries
- Achieving Excellent Image Quality in CT of the Coronary Arteries
- CT Angiography of the Coronary Arteries
4 Image Reconstruction
- Planimetric Techniques
- Volumetric Techniques (Volume Rendering)
- Virtual Endoscopy
5 Coronary Pathophysiology
- Coronary Flow Reserve
- Coronary Stenosis: Definition and Evaluation in Coronary Artery Disease
- The Limits of Coronary Angiography
6 The Atherosclerotic Plaque
- The Vulnerable Plaque: Biology and Histology
- The Vulnerable Plaque: Local and Systemic Factors Contributing to Plaque Rupture
7 Intravascular Ultrasound: From Gray-Scale to Virtual Histology
- Introduction
- From Gray-Scale to Color-Coded IVUS: The Virtual-Histology Revolution
- Lesion Classification Using IVUS-VH
- IVUS-VH Console and Image Interpretation: Tips and Tricks
8 Identification and Characterization of the Atherosclerotic Plaque Using Coronary CT Angiography
- Normal Vascular Wall
- Identification of Atherosclerotic Plaques in Coronary CT Angiography
- CT Density Values and Plaque Characterization: Fibrolipidic and Calcific Plaques
- Atherosclerotic Plaque and Disease Evolution
- Diagnostic Evaluation of Coronary Disease During Medical Therapy
9 Coronary CT Angiography: Evaluation of Stenosis and Occlusion
- Non-Significant Moderate Stenosis
- Calcified Plaques: Problems in Defining Vascular Stenosis
- Significant Stenosis
- Remodeling
- Occlusion of the Coronary Arteries and the Development of Collateral Circulatio
- Evaluation of Coronary-Artery Stenosis: A Review of the Literature
- Saving Lives
10 Current Strategies in Cardiac Surgery
- Standard Grafting Techniques
- Results
11 Coronary CT Angiography: Evaluation of Coronary Artery Bypass Grafts
- Pre-Operative CT Evaluation
- Post-Operative Evaluation of CABG
- CT Evaluation of CABG: Technique
- CT Evaluation of CABG: Results
12 Coronary Stents
- Types of Stents
- Mechanism of Stent Expansion
- Materials
- Fabrication Methods
- Additions
- Impact of Stent Design on Clinical Outcome
- Bioabsorbable and Biocompatible Stents
13 CT Angiography of Coronary Stents
14 X-ray Exposure in Coronary CT Angiography
- Damage from Ionizing Radiation
- X-ray Dose During CT
- Techniques for Limiting X-ray Exposure in Coronary CT Angiography
- X-ray Exposure and Patient Age
15 Use of MSCT Scanning in the Emergency-Room Evaluation of Patients with Chest Pain
- Causes of Acute Chest Pain
- Multislice CT Scanning in Acute Chest Pain
- The “Triple Rule Out” Protocol
16 Current Recommendations for Coronary CT Angiography
- Technical Considerations
- Evaluation of Coronary Stenoses in Patients at Low or Intermediate Risk of Cardiovascular Disease
- Evaluation of Coronary-Artery Bypass Patency
- Other Frequent Uses of Coronary CT Angiography
- Contraindications to Coronary CT Angiography
- Future Directions in Non-invasive Coronary Artery Imaging with Coronary CT Angiography
17 Prognostic Value of Coronary CT
Suggested Readings
Originally published as:
Malattia coronarica
Fisiopatologia e diagnostica non invasiva con TC
Paolo Pavone, Massimo Fioranelli
© Springer-Verlag Italia 2008
All rights reserved
Le malattie cardiovascolari rappresentano attualmente la causa principale di mortalità e, oltre a modificare sensibilmente la qualità della vita, comportano un notevole impegno economico per la società. Poiché la maggior parte degli eventi coronarici si verifica per la complicanza di una placca aterosclerotica parietale non stenosante, il suo riconoscimento può assumere rilevante significato clinico ed essere di interesse nella scelta di un trattamento medico o interventistico.
Attraverso l’utilizzo di apparecchiature sempre più sensibili e veloci, oggi la TC coronarica ci consente, finalmente, di visualizzare la lesione responsabile delle sindromi coronariche acute e di caratterizzarla. La conoscenza delle apparecchiature, la valutazione dei loro limiti e l’adeguata preparazione del paziente, rappresentano passaggi importanti per l’ottenimento di immagini adeguate dal punto di vista diagnostico.
L’opera nasce dalla volontà di fornire al cardiologo o al medico non esperto di imaging le basi per comprendere principi tecnici e modalità di acquisizione e di ricostruzione delle immagini. Allo stesso tempo anche il radiologo che non abbia esperienze specifiche di imaging cardiaco potrà acquisire conoscenze di base di anatomia e fisiopatologia delle coronarie.