The fields of gastroenterology and hepatology have changed dramatically in the past ten years, partially as a result of the impressive advances in understanding the molecular and pathophysiologic basis of gastrointestinal disorders. Such advances have spawned translational research, which in turn has resulted in important new diagnostic and therapeutic modalities. In addition, the expanding knowledge base has resulted in the development of sub-subspecialties within the fields of gastroenterology and hepatology, such as liver transplantation, pancreatic disease, inflammatory bowel disease, and motility disorders. Several topics in these disciplines are discussed in detail in Current Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy. Most notably, an entire section of the book is devoted to advances in diagnostic and therapeutic endoscopy.
As a specialty, gastroenterology interfaces with other medical and surgical sub-specialties, specifically gastrointestinal surgery, gastrointestinal radiology, and gastrointestinal pathology. Accordingly, several of the chapters in this book deal with important information in these related specialties. A comprehensive chapter on gastrointestinal radiology includes over 50 images that help clarify the appropriate use of the many imaging techniques currently available. Gastrointestinal disorders that have surgical implications, such as bariatric surgery and inflammatory bowel disease, are presented in detail. The chapter on bariatric surgery highlights the advances in this field that have led to over 100,000 bariatric surgical procedures performed every year. With over 1.5 million patients in the United States with inflammatory bowel disease, surgical considerations for these disorders have become increasingly important.
This book strikes the right balance between comprehensiveness and convenience. It emphasizes the practical aspects of diagnosis of gastrointestinal and hepatic disorders, with each chapter outlining the essentials of diagnosis of various disorders. Current Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy provides concise, complete, and accessible clinical information that is up-to-date.
A unique feature of this book is that virtually all of the authors are faculty members at the Harvard Medical School and Brigham and Women’s Hospital. Importantly, it has been possible for the editor and associate editors to work closely with all the authors to assure uniformity of presentation as well as clarity and relevance. The intended audience for which this book has been written comprises gastroenterologists, general internists, family physicians, and surgeons, all of whom can derive benefit from the easily accessible, up-to-date information that this book offers on diagnosis and treatment in gastroenterology, hepatology, and endoscopy.
About the Editor
Norton J. Greenberger, MD
Clinical Professor of Medicine, Harvard Medical School
Senior Physician, Division of Gastroenterology, Hepatology and Endoscopy
Brigham and Women’s Hospital
Boston, Massachusetts
Richard S. Blumberg, MD
Professor of Medicine, Harvard Medical School
Chief, Division of Gastroenterology, Hepatology and Endoscopy
Brigham and Women’s Hospital
Boston, Massachusetts
Robert Burakoff, MD, MPH
Associate Professor of Medicine, Harvard Medical School
Clinical Chief of Gastroenterology, Division of Gastroenterology and Hepatology
Brigham and Women’s Hospital
Boston, Massachusetts
Contents
Section I. General Concerns
1. Acute Abdominal Pain: Basic Principles & Current Challenges
2. Inflammatory Bowel Disease: Immunologic Considerations
3. Inflammatory Bowel Disease: Medical Considerations
4. Inflammatory Bowel Disease: Surgical Considerations
5. Acute Diarrheal Disorders
6. Mesenteric Ischemia
7. Gastrointestinal & Biliary Complications of Pregnancy
8. Hepatic Complications of Pregnancy
9. State-of-the Art Imaging of the Gastrointestinal System
10. Gastrointestinal Manifestations of Immunodeficiency
Section II. Esophageal Diseases
11. Gastroesophageal Reflux Disease
12. Barrett Esophagus
13. Oropharyngeal & Esophageal Motility Disorders
14. Eosinophilic Esophagitis
Section III. Diseases of the Stomach
15. Peptic Ulcer Disease
16. Zollinger-Ellison Syndrome (Gastrinoma)
17. Functional (Nonulcer) Dyspepsia
18. Disorders of Gastric & Small Bowel Motility
19. Treatment of Obesity: The Impact of Bariatric Surgery
Section IV. Small Bowel Diseases
20. Intestinal Malabsorption
Section V. Colorectal Diseases
21. Diverticular Disease of the Colon
22. Colorectal Cancer Screening
23. Hereditary Gastrointestinal Cancer Syndromes
24. Irritable Bowel Syndrome
Section VI. Pancreatic Diseases
25. Acute Pancreatitis
26. Chronic Pancreatitis
27. Autoimmune Pancreatitis
28. Tumors of the Pancreas
Section VII. Therapeutic Endoscopy & Novel Diagnostic Techniques
29. Polypectomy
30. Acute Upper Gastrointestinal Bleeding
31. Acute Lower Gastrointestinal Bleeding
32. Endoscopic Management of Acute Biliary & Pancreatic Conditions
33. Wireless Capsule Endoscopy & Double-Balloon Enteroscopy
34. Gastrointestinal Foreign Bodies
35. Endoscopic Retrograde Cholangiopancreatography (ERCP)
36. Endoscopic Ultrasound
Section VIII. Liver Diseases
37. Approach to the Patient with Jaundice & Abnormal Liver Tests
38. Acute Liver Failure
39. Viral Hepatitis
40. Chronic Nonviral Hepatitis
41. Hereditary Hemochromatosis
42. Alcoholic Liver Disease
43. Nonalcoholic Fatty Liver Disease
44. Portal Systemic Encephalopathy & Hepatic Encephalopathy
45. Ascites & Spontaneous Bacterial Peritonitis
46. Hepatorenal Syndrome
47. Portal Hypertension & Esophageal Variceal Hemorrhage
48. Drug-Induced Liver Disease
49. Liver Neoplasms
50. Liver Transplantation
51. Primary Biliary Cirrhosis
Section IX. Biliary Tract Diseases
52. Primary Sclerosing Cholangitis
53. Gallstone Disease
Index
As a specialty, gastroenterology interfaces with other medical and surgical sub-specialties, specifically gastrointestinal surgery, gastrointestinal radiology, and gastrointestinal pathology. Accordingly, several of the chapters in this book deal with important information in these related specialties. A comprehensive chapter on gastrointestinal radiology includes over 50 images that help clarify the appropriate use of the many imaging techniques currently available. Gastrointestinal disorders that have surgical implications, such as bariatric surgery and inflammatory bowel disease, are presented in detail. The chapter on bariatric surgery highlights the advances in this field that have led to over 100,000 bariatric surgical procedures performed every year. With over 1.5 million patients in the United States with inflammatory bowel disease, surgical considerations for these disorders have become increasingly important.
This book strikes the right balance between comprehensiveness and convenience. It emphasizes the practical aspects of diagnosis of gastrointestinal and hepatic disorders, with each chapter outlining the essentials of diagnosis of various disorders. Current Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy provides concise, complete, and accessible clinical information that is up-to-date.
A unique feature of this book is that virtually all of the authors are faculty members at the Harvard Medical School and Brigham and Women’s Hospital. Importantly, it has been possible for the editor and associate editors to work closely with all the authors to assure uniformity of presentation as well as clarity and relevance. The intended audience for which this book has been written comprises gastroenterologists, general internists, family physicians, and surgeons, all of whom can derive benefit from the easily accessible, up-to-date information that this book offers on diagnosis and treatment in gastroenterology, hepatology, and endoscopy.
About the Editor
Norton J. Greenberger, MD
Clinical Professor of Medicine, Harvard Medical School
Senior Physician, Division of Gastroenterology, Hepatology and Endoscopy
Brigham and Women’s Hospital
Boston, Massachusetts
Richard S. Blumberg, MD
Professor of Medicine, Harvard Medical School
Chief, Division of Gastroenterology, Hepatology and Endoscopy
Brigham and Women’s Hospital
Boston, Massachusetts
Robert Burakoff, MD, MPH
Associate Professor of Medicine, Harvard Medical School
Clinical Chief of Gastroenterology, Division of Gastroenterology and Hepatology
Brigham and Women’s Hospital
Boston, Massachusetts
Contents
Section I. General Concerns
1. Acute Abdominal Pain: Basic Principles & Current Challenges
2. Inflammatory Bowel Disease: Immunologic Considerations
3. Inflammatory Bowel Disease: Medical Considerations
4. Inflammatory Bowel Disease: Surgical Considerations
5. Acute Diarrheal Disorders
6. Mesenteric Ischemia
7. Gastrointestinal & Biliary Complications of Pregnancy
8. Hepatic Complications of Pregnancy
9. State-of-the Art Imaging of the Gastrointestinal System
10. Gastrointestinal Manifestations of Immunodeficiency
Section II. Esophageal Diseases
11. Gastroesophageal Reflux Disease
12. Barrett Esophagus
13. Oropharyngeal & Esophageal Motility Disorders
14. Eosinophilic Esophagitis
Section III. Diseases of the Stomach
15. Peptic Ulcer Disease
16. Zollinger-Ellison Syndrome (Gastrinoma)
17. Functional (Nonulcer) Dyspepsia
18. Disorders of Gastric & Small Bowel Motility
19. Treatment of Obesity: The Impact of Bariatric Surgery
Section IV. Small Bowel Diseases
20. Intestinal Malabsorption
Section V. Colorectal Diseases
21. Diverticular Disease of the Colon
22. Colorectal Cancer Screening
23. Hereditary Gastrointestinal Cancer Syndromes
24. Irritable Bowel Syndrome
Section VI. Pancreatic Diseases
25. Acute Pancreatitis
26. Chronic Pancreatitis
27. Autoimmune Pancreatitis
28. Tumors of the Pancreas
Section VII. Therapeutic Endoscopy & Novel Diagnostic Techniques
29. Polypectomy
30. Acute Upper Gastrointestinal Bleeding
31. Acute Lower Gastrointestinal Bleeding
32. Endoscopic Management of Acute Biliary & Pancreatic Conditions
33. Wireless Capsule Endoscopy & Double-Balloon Enteroscopy
34. Gastrointestinal Foreign Bodies
35. Endoscopic Retrograde Cholangiopancreatography (ERCP)
36. Endoscopic Ultrasound
Section VIII. Liver Diseases
37. Approach to the Patient with Jaundice & Abnormal Liver Tests
38. Acute Liver Failure
39. Viral Hepatitis
40. Chronic Nonviral Hepatitis
41. Hereditary Hemochromatosis
42. Alcoholic Liver Disease
43. Nonalcoholic Fatty Liver Disease
44. Portal Systemic Encephalopathy & Hepatic Encephalopathy
45. Ascites & Spontaneous Bacterial Peritonitis
46. Hepatorenal Syndrome
47. Portal Hypertension & Esophageal Variceal Hemorrhage
48. Drug-Induced Liver Disease
49. Liver Neoplasms
50. Liver Transplantation
51. Primary Biliary Cirrhosis
Section IX. Biliary Tract Diseases
52. Primary Sclerosing Cholangitis
53. Gallstone Disease
Index