PART I. INTRODUCTION.
- 1. Dynamic Imaging of Brain Function.
- 2. Fractal Characterization of Complexity in Dynamic Signals: Application to Cerebral Hemodynamics.
PART II. OPTICAL IMAGING.
- 3. Wide-Field and Two-Photon Imaging of Brain Activity with Voltageand Calcium-Sensitive Dyes.
- 4. Two-Photon Imaging of Capillary Blood Flow in Olfactory Bulb Glomeruli.
- 5. Astrocytic Calcium Signaling: Mechanism and Implications for Functional Brain Imaging.
- 6. Using the Light Scattering Component of Optical Intrinsic Signals to Visualize In Vivo Functional Structures of Neural Tissues.
PART III. ELECTROPHYSIOLOGY
- 7. Methods for Studying Functional Interactions Among Neuronal Populations.
- 8. Magnetoencephalography (MEG).
- 9. Functional Neuroimaging of Spike-Wave Seizures.
PART IV. FUNCTIONAL MAGNETIC RESONANCE IMAGING (fMRI)
- 10. Tactile and Non-tactile Sensory Paradigms for fMRI and Neurophysiologic Studies in Rodents.
- 11. Using fMRI for Elucidating Dynamic Interactions.
- 12. Resting-State Functional Connectivity in Animal Models: Modulations by Exsanguination.
PART V. ALTERNATE MAGNETIC RESONANCE METHODS
- 13. Dynamic Magnetic Resonance Imaging of Cerebral Blood Flow Using Arterial Spin Labeling.
- 14. Dynamic MRI of Small Electrical Activity.
- 15. Advanced In Vivo Heteronuclear MRS Approaches for Studying Brain Bioenergetics Driven by Mitochondria.
Index.
Dynamic Brain Imaging: Multi-Modal Methods and In Vivo Applications will help users learn to decipher the dynamic imaging data that will be critical to our future understanding of complex brain functions.
In recent years, there have been unprecedented methodological advancements in the imaging of brain activity. These techniques allow the measurement of everything from neural activity (e.g., membrane potential, ion flux, neurotransmitter flux) to energy metabolism (e.g., glucose consumption, oxygen consumption, creatine kinase flux) and functional hyperemia (e.g., blood flow, volume, oxygenation). This book deals with a variety of magnetic resonance, electrophysiology, and optical methods that are often used to measure some of these dynamic processes.
All chapters were written by leading experts, spanning three continents, specializing in state-of-the-art methods. Briefly, the book has five sections. In the introductory section, there are two chapters; the first one contains a brief preamble to dynamic brain imaging and the other presents a novel, analytical approach to processing of dynamically acquired data. The second section has four chapters and delves into a wide range of optical imaging methods. The next two sections have three chapters each, whereas the last section has four chapters. The third section discusses many of the most frequently used electrophysiological methods. The fourth section presents diverse uses and applications of functional magnetic resonance imaging (fMRI). The final section brings together some up-and-coming alternate magnetic resonance methods with the potential to strengthen non-invasive neuroimaging.
Key Features
- Provides a balanced emphasis on methods and applications that even specialists within various functional imaging fields will find useful.
- Contains a review of developments in technical features of dynamic multi-modal imaging and analytical tools for characterization of dynamic signals.
- Includes novel multi-modal applications in neuroimaging to epilepsy, with state-of-the-art demonstrations of increased sensitivity and specificity of detection.
- Examines examples of dynamic functional imaging of multiple brain areas (e.g., cerebral cortex, olfactory bulb, retina) using cutting-edge multi-modal techniques.
Book Details
- Hardcover: 366 pages
- Publisher: Humana Press; 1 edition (October 23, 2008)
- Language: English
- ISBN-10: 1934115746
- ISBN-13: 978-1934115749
- Product Dimensions: 10.4 x 7.4 x 0.9 inches
List Price: $99.00