PET/CT epitomizes a marriage made in imaging heaven. The ability of PET to image cellular metabolism combined with the anatomic detail of CT represents a transformational approach to imaging neoplasia and other diseases. The task of PET/CT image interpretation is also challenging. This stems from the need to be highly skilled in both nuclear medicine and body/brain imaging. The impact of this technology hasbeen enormous in cancer, Alzheimer’s disease, and epilepsy; now representing an integral component of the standard workup and management of these patients.
This book aims to provide a thorough understanding of the technical demands involved in combining CT and FDG PET: patient preparation, acquisition techniques including potential pitfalls and limitations, and the basics of instrumentation and physics needed for developing cogent technical approaches. Technical advances and controversies including the use of CT contrast and, when clinically relevant, newer radiopharmaceuticals (beyond the most clinically available 18F-2-deoxy-fluoro-D-glucose or FDG) are addressed briefly.
The raison d’etre of this work is to offer the practicing nuclear medicine physician/ radiologist a thorough understanding of the clinical application of these dedicated PET/CT scanners to oncology and neurologic disease. Whenever possible, the place of PET/CT in the diagnostic algorithm is explored and with it the particular information provided by both FDG PET and CT for the analysis of a particular diagnostic problem. When clinical questions remain even after PET/CT, further answers may come from other anatomic or functional imaging.
In this context, the author have attempted to provide a comprehensive, disease-oriented approach to PET/CT. The diagnostic setting in which PET/CT will prove most valuable have reviewed, the PET findings, literature-based evidence for utility, applications, and limitations to each disease and specific clinical settings related to that disease. In each section we have attempted to include CT findings that will bear on the PET interpretation and vice versa. It is our hope that this book will provide a practical, comprehensive guide for the imagers on the front line of clinical diagnosis and management of cancer and central nervous system diseases.
Position Emission Tomography-Computed Tomography: A Disease-Oriented Approach will serve as a most useful and lucid reference for those engaged in learning and using PET/CT.
About the Author
Contents
Principles of PET/CT (for QA)
1. Technical Aspects of CT in Practice
2. PET Instrumentation and Methodology
3. Patient Preparation and Scanning Considerations for PET and PET/CT
Brain Imaging
4. Clinical PET/CT in the Brain
Head and Neck
5. Head and Neck Cancers: Evaluation with PET/CT
6. PET and PET/CT of Thyroid Disease
Chest
7. PET/CT: Mediastinal Lesions
8. Diseases of the Lungs and Pleura: FDG PET/CT
9. PET/CT in Breast Cancer
Abdomen
10. PET/CT for the Evaluation of Diseases of Gastrointestinal Origin
11. PET/CT in Gynecologic Malignancies
12. Using PET/CT in Evaluating Cancers of the Genitourinary Tract
Musculoskeletal
13. Detecting and Evaluating Osseous Metastases on PET/CT
14. PET/CT Findings in Primary Bone Tumors
15. PET/CT Evaluation of Soft Tissue Sarcoma
Melanoma and Other Skin Cancers
16. PET/CT Imaging of Cutaneous Malignancies
Hematopoietic Malignancies
17. PET/CT in Evaluating Lymphoma
Index
This book aims to provide a thorough understanding of the technical demands involved in combining CT and FDG PET: patient preparation, acquisition techniques including potential pitfalls and limitations, and the basics of instrumentation and physics needed for developing cogent technical approaches. Technical advances and controversies including the use of CT contrast and, when clinically relevant, newer radiopharmaceuticals (beyond the most clinically available 18F-2-deoxy-fluoro-D-glucose or FDG) are addressed briefly.
The raison d’etre of this work is to offer the practicing nuclear medicine physician/ radiologist a thorough understanding of the clinical application of these dedicated PET/CT scanners to oncology and neurologic disease. Whenever possible, the place of PET/CT in the diagnostic algorithm is explored and with it the particular information provided by both FDG PET and CT for the analysis of a particular diagnostic problem. When clinical questions remain even after PET/CT, further answers may come from other anatomic or functional imaging.
In this context, the author have attempted to provide a comprehensive, disease-oriented approach to PET/CT. The diagnostic setting in which PET/CT will prove most valuable have reviewed, the PET findings, literature-based evidence for utility, applications, and limitations to each disease and specific clinical settings related to that disease. In each section we have attempted to include CT findings that will bear on the PET interpretation and vice versa. It is our hope that this book will provide a practical, comprehensive guide for the imagers on the front line of clinical diagnosis and management of cancer and central nervous system diseases.
Position Emission Tomography-Computed Tomography: A Disease-Oriented Approach will serve as a most useful and lucid reference for those engaged in learning and using PET/CT.
About the Author
- ELISSA L. KRAMER is currently an adjunct Professor of Radiology at New York University, School of Medicine, New York. She retired in February 2007 from her clinical position where she served as Section Chief of Nuclear Medicine. She received her M.D. from New York University where she completed her residency in Radiology and her fellowship in Nuclear Medicine at New York University Medical Center and Bellevue Hospital Center, New York. Dr. Kramer has published on Nuclear Medicine imaging in the immunosuppressed patient and on the clinical application of SPECT. Her research interests are tumor imaging, including clinical FDG PET and SPECT, image fusion, and lymphoscintigraphy, both for lymphedema and sentinel node identification.
- JANE P. KO is Associate Professor of Radiology, Thoracic Imaging Section, New York University School of Medicine, and an Associate Attending at Tisch and Bellevue Hospitals at New York University Medical Center, New York. She received her M.D. from University of Chicago, Pritzker School of Medicine, Chicago, Illinois, and completed a fellowship in the Thoracic Section of the Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Dr. Ko’s major areas of clinical and research interest cover image analysis technology, chest CT, and lung cancer/chest malignancy. She is a member of the editorial board of the Journal of Thoracic Imaging, and has published over 30 peer-reviewed and educational manuscripts and three book chapters.
- FABIO PONZO is Assistant Professor of Radiology, New York University School of Medicine, New York, Clinical Assistant Attending, Department of Radiology, Nuclear Medicine, New York University School of Medicine, Clinical Assistant Attending, Department of Radiology, Nuclear Medicine, Tisch Hospital/New York University Medical Center, Assistant Attending, Department of Radiology, Nuclear Medicine, Bellevue Hospital Medical Center, New York. Dr. Ponzo received his M.D. from the University of Rome, La Sapienza Medical School, Italy, and then served as an M.D. Officer for the Italian Air Force. He completed his residency in Nuclear Medicine from both the University of Rome, and University of Pennsylvania, Philadelphia, and his major area of interest is in Nuclear Medicine.
- KAREN MOURTZIKOS is Assistant Professor of Radiology, Division of Nuclear Medicine, New York University School of Medicine, New York, Assistant Attending of Radiology, Division of Nuclear Medicine, New York University Hospitals Center, New York, and Assistant Attending of Radiology, Division of Nuclear Medicine, Bellevue Hospital, New York. Dr. Mourtzikos received her M.D. from Albany Medical College, completed her residency in nuclear medicine from the University of Maryland, Baltimore, and a fellowship in Clinical and Research PET and PET/CT, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Contents
Principles of PET/CT (for QA)
1. Technical Aspects of CT in Practice
2. PET Instrumentation and Methodology
3. Patient Preparation and Scanning Considerations for PET and PET/CT
Brain Imaging
4. Clinical PET/CT in the Brain
Head and Neck
5. Head and Neck Cancers: Evaluation with PET/CT
6. PET and PET/CT of Thyroid Disease
Chest
7. PET/CT: Mediastinal Lesions
8. Diseases of the Lungs and Pleura: FDG PET/CT
9. PET/CT in Breast Cancer
Abdomen
10. PET/CT for the Evaluation of Diseases of Gastrointestinal Origin
11. PET/CT in Gynecologic Malignancies
12. Using PET/CT in Evaluating Cancers of the Genitourinary Tract
Musculoskeletal
13. Detecting and Evaluating Osseous Metastases on PET/CT
14. PET/CT Findings in Primary Bone Tumors
15. PET/CT Evaluation of Soft Tissue Sarcoma
Melanoma and Other Skin Cancers
16. PET/CT Imaging of Cutaneous Malignancies
Hematopoietic Malignancies
17. PET/CT in Evaluating Lymphoma
Index
Book Details
- Hardcover: 480 pages
- Publisher: Informa Healthcare
- Language: English
- ISBN-10: 0849380871
- ISBN-13: 978-0849380877
- Product Dimensions: 11 x 8.7 x 1.1 inches